![]() ![]() “Primarily what we’re seeing is people who are using multiple substances,” said Kehoe, who is medical director at the Massachusetts General Hospital Bridge Clinic. Laura Kehoe says while she’s excited about getting help with meth treatment, she doesn’t expect to begin frequent prescriptions of these two drugs. It essentially pushes anyone who’s taken an opioid, including a very low dose medication like buprenorphine, into immediate withdrawal. Naltrexone, one of the two drugs in this study, blocks opioid receptors. (Massachusetts Department of Health)īut this drug combination might not work for people like Leslie who sometimes used meth in combination with an opioid. “To see the state of meth right now and how it continues to rise, there’s no better time to come up with a breakthrough like this,” Leslie said. In Boston, where Leslie supervises recovery coaches, he says meth use is rampant. In Massachusetts, where Mike Leslie is in recovery from addictions to several drugs, fatal overdoses involving meth and other psychostimulants have risen more than 400% since 2000. The results are particularly important now, says Volkow, when the latest CDC figures indicate deaths tied to meth use increased 35% in one year. Nora Volkow, director of the National Institute on Drug Abuse (NIDA). “It’s the first time we have a large trial showing such a clear signal of therapeutic benefit, so it’s a big deal,” said Dr. “It’s the first time we have a large trial showing such a clear signal of therapeutic benefit, so it’s a big deal." Dr. It’s a modest percentage but still more than five times greater than participants who received a placebo. Among the 403 study participants, nearly 14% of those who took the combo presented mostly drug-free urine samples. That starts to change today with the publication of a study through which meth users received a combination of two approved drugs, an antidepressant and naltrexone, which is prescribed for addictions to opioids and alcohol. There are no accepted medications that help patients resist the intense cravings. In the world of addiction treatment, many specialists say meth is their most formidable challenge. ![]() Methamphetamine use and resulting overdose deaths are devastating families in cities and towns across the U.S. Other environmental influences include having an unstable home life during childhood and associating with individuals who abuse amphetamines.Facebook Email This article is more than 2 years old. Heritable traits such as impulsivity can also increase a person’s risk for stimulant use disorder.Įnvironmental: Being prescribed a medication that contains amphetamine can be an environmental influence on the development of amphetamine abuse and addiction, as can early exposure to amphetamines and ease of access to such drugs. Family history of mental illness and substance abuse is a strong predictor of future problems with a stimulant use disorder. Genetic: Research strongly suggests that genetics play a significant role in determining whether or not a person will struggle with substance abuse and addiction. The following are examples of genetic and environmental factors that may influence a person’s likelihood of engaging in amphetamine abuse. Causes and risk factors for amphetamine addiction ![]()
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